ncRNA name | hsa-miR-497 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples; RB cell lines Y79 and WERI-RB1 |
Methods | transfection, qRT-PCR, CCK-8 assay, transwell assay, Western blot, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | miR-497 functions as a tumor suppressor in the carcinogenesis and progression of retinoblastoma via targeting VEGFA. |
PubMed ID | 28588740 |
Year | 2017 |
Title | microRNA-497 overexpression decreases proliferation, migration and invasion of human retinoblastoma cells via targeting vascular endothelial growth factor A. |
Drug-related ncRNA | NO |
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