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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-497
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples; RB cell lines Y79 and WERI-RB1
Methods transfection, qRT-PCR, CCK-8 assay, transwell assay, Western blot, luciferase reporter assay
Expression pattern down-regulated
Functional description miR-497 functions as a tumor suppressor in the carcinogenesis and progression of retinoblastoma via targeting VEGFA.
PubMed ID 28588740
Year 2017
Title microRNA-497 overexpression decreases proliferation, migration and invasion of human retinoblastoma cells via targeting vascular endothelial growth factor A.
Drug-related ncRNA NO

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